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  Indian J Med Microbiol
 

Figure 3: Serum stability of siRNA (A & B) and nanoparticles mediated transfection (C & D): (A) Serum stability of naked siRNA2; (B) Serum stability of siRNA2-loaded chitosan coated polylactic-co-glycolic acid (PLGA) nanoparticles incubated in 10 per cent of foetal bovine serum over a period of time; (C) Chitosan-coated PLGA nanoparticle-mediated siRNA2 transfection in HeLa cells (Phase contrast); (D) Chitosan-coated PLGA nanoparticle-mediated siRNA2 transfection in HeLa cell emitted fluorescence due to cy3 labelling with siRNA.

Figure 3: Serum stability of siRNA (A & B) and nanoparticles mediated transfection (C & D): (A) Serum stability of naked siRNA2; (B) Serum stability of siRNA2-loaded chitosan coated polylactic-co-glycolic acid (PLGA) nanoparticles incubated in 10 per cent of foetal bovine serum over a period of time; (C) Chitosan-coated PLGA nanoparticle-mediated siRNA2 transfection in HeLa cells (Phase contrast); (D) Chitosan-coated PLGA nanoparticle-mediated siRNA2 transfection in HeLa cell emitted fluorescence due to cy3 labelling with siRNA.