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Figure 2: Microscopic sections of adrenal glands show a tiny fragment of adrenal tissue with focal neutrophilic infiltration. No granuloma or histiocytes were noted. Mild vascular proliferation was seen. No atypical cells were noted. (A) Hematoxylin-eosin stain × 400 showing Histoplasma arranged in sheets, both inside the macrophages and extracellulary. (B) PAS stain (periodic acid Schiff stain) × 400: shows focal ovoid bodies with a clear halo which represents the fungal spores and organisms (arrow). |
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