Figure 2: Differential elevations of chemokine receptors and maturation markers in dendritic cell (DC) subtypes before and after therapy. SOO2 is screening visit 2, 2 wk before initiation of therapy. FU24 is 24 wk after cessation of treatment. Median fluorescence intensity (MFI) values for each patient are shown. The horizontal line is the median. A two-tailed non parametric Wilcoxon signed rank test was used for paired data or the two-tailed Mann-Whitney test was used to calculate P values. (B) CD83 MFI on plasmacytoid and myeloid DCs (pDCs, mDCs); CD40 MFI for pDCs, mDCs; HLA-DR for pDCs and mDCs. SVR, sustained virological response. (Reproduced with permission from British Medical Association, London, UK [Gut 2009; 58 : 964-73]74.