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   2009| January  | Volume 129 | Issue 1  
    Online since April 20, 2011

 
 
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ORIGINAL ARTICLES
An increase in enteric fever cases due to Salmonella Paratyphi A in & around Chandigarh
V Gupta, J Kaur, J Chander
January 2009, 129(1):95-98
PMID:19287065
Full text not available  [PDF]  [PubMed]
  81 332 -
REVIEW ARTICLES
Animal models of tuberculosis for vaccine development
UD Gupta, VM Katoch
January 2009, 129(1):11-18
PMID:19287053
Animal models for testing different vaccine candidates have been developed since a long time for studying tuberculosis. Mice, guinea pigs and rabbits are animals most frequently used. Each model has its own merits for studying human tuberculosis, and none completely mimics the human disease. Different animal models are being used depending upon the availability of the space, trained manpower as well as other resources. Efforts should continue to develop a vaccine which can replace/outperform the presently available vaccine BCG.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  286 126 -
ORIGINAL ARTICLES
Ectopic Cushing's syndrome : experience from a tertiary care centre
A Bhansali, R Walia, SS Rana, P Dutta, BD Radotra, N Khandelwal, SK Bhadada
January 2009, 129(1):33-41
PMID:19287055
Full text not available  [PDF]  [PubMed]
  149 245 -
Establishment of T-lymphocyte subset reference intervals in a healthy adult population in Chennai, India
KG Murugavel, P Balakrishnan, J Mohanakrishnan, SS Solomon, EM Shankar, Sandeep Pulimi Muthu Sundaram, N Kumarasamy, E Piwowar-Manning, E Livant, KH Mayer, SP Thyagarajan, S Solomon
January 2009, 129(1):59-63
PMID:19287058
Estimation of CD4+ T-lymphocytes continues to be an important aspect for monitoring HIV disease progression and response to antiretroviral therapy. Most of the diagnostic laboratories often rely on western text books for CD4+ T-lymphocyte reference values, which could, often be unreliable for usage in local settings. Therefore, we attempted to establish the reference values for T-lymphocyte subsets among healthy adults in a cross-sectional study carried out at the YRG Centre for AIDS Research and Education (YRG CARE) in Chennai, south India, in 213 (84 female and 129 male) healthy, HIV-1/2 seronegative adults as volunteers. Whole blood specimens were processed for CD4+, CD8+ T-lymphocyte estimation and haematological parameters. The established range of CD4+ T-lymphocyte counts for men and women were 383-1347 cells/microl (mean 865 and median 845 cells/microl) and 448-1593 cells/microl (mean 1021 and median 954 cells/microl), respectively. Women had significantly higher absolute CD4+ Tlymphocyte counts (P<0.001) and CD4+:CD8+ T-lymphocyte ratio as compared to men. The established normal range of CD4+ T-lymphocyte % was 21-59 (mean 40.2 and median 40.1). The influence of age was not observed in any of the parameters except CD4+/CD8+ T-lymphocyte ratio with the >45 yr age group. Further studies with greater sample size may be required to define the staging of HIV disease in relation to the normal CD4 T-lymphocyte count in the general population.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  252 106 -
REVIEW ARTICLES
Informed consent & ethical issues in paediatric psychopharmacology
S Malhotra, BN Subodh
January 2009, 129(1):19-32
PMID:19287054
Issues relating to informed consent and ethics in paediatric psychopharmacology limit research in this population. Children vary in their levels of cognitive development, and presence of psychiatric disorder may further impair their ability to give informed consent. In decisional impairment subjects, various methods used for consent are assent/dissent; inclusion of advance directives; and/or alternative decision-makers. India is emerging as a new market for clinical trials in recent years. Moreover, in India the sociocultural realities are different from those in the western countries making it necessary for professionals to be cautious in conducting drug trials. In this review, issues regarding informed consent in children and adolescent with psychiatric diagnosis are discussed for information, discussion and debate by professionals, parents, society and legal experts to create awareness and to facilitate development of guidelines that are appropriate and applicable to the Indian system.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  233 122 -
ORIGINAL ARTICLES
Improved estimates of India's HIV burden in 2006
A Pandey, Dandu C Reddy, Peter D Ghys, M Thomas, D Sahu, M Bhattacharya, Kanchan D Maiti, F Arnold, S Kant, A Khera, R Garg
January 2009, 129(1):50-58
PMID:19287057
Full text not available  [PDF]  [PubMed]
  126 203 -
Role of acute viral hepatitis as a confounding factor in antituberculosis treatment induced hepatotoxicity
P Sarda, SK Sharma, A Mohan, G Makharia, A Jayaswal, RM Pandey, S Singh
January 2009, 129(1):64-67
PMID:19287059
Full text not available  [PDF]  [PubMed]
  128 128 -
An exploratory clinical study of adult attention deficit/hyperactivity disorder from India
P Sitholey, V Agarwal, S Sharma
January 2009, 129(1):83-88
PMID:19287063
Full text not available  [PDF]  [PubMed]
  91 162 -
Addition of isovitalex in chocolate agar for the isolation of Haemophilus influenzae
SK Saha, AH Baqui, GL Darmstadt, M Islam, SE Arifeen, M Santosham, T Nagatake, RE Black
January 2009, 129(1):99-101
PMID:19287066
Full text not available  [PDF]  [PubMed]
  138 113 -
Demographic & clinical profile of HIV infected children accessing care at Tambaram, Chennai, India
S Rajasekaran, L Jeyaseelan, K Raja, N Ravichandran
January 2009, 129(1):42-49
PMID:19287056
Full text not available  [PDF]  [PubMed]
  123 96 -
CORRESPONDENCES
Association of mutations in rpsL gene with high degree of streptomycin resistance in clinical isolates of Mycobacterium tuberculosis in India
R Das, P Gupta, P Singh, DS Chauhan, K Katoch, VM Katoch
January 2009, 129(1):108-110
PMID:19287069
Full text not available  [PDF]  [PubMed]
  103 101 -
EDITORIAL
Shift to Th2 cytokine response in dengue haemorrhagic fever
UC Chaturvedi
January 2009, 129(1):1-3
PMID:19287050
Full text not available  [PDF]  [PubMed]
  91 110 -
CORRESPONDENCES
Newer strategies for the kala-azar elimination programme in India
CP Thakur, Amit Kumar Meenakshi Thakur, S Thakur
January 2009, 129(1):102-104
PMID:19287067
Full text not available  [PDF]  [PubMed]
  91 109 -
PCR on formalin-fixed necropsy tissues to diagnose leptospirosis
V Manu, S Roy, Anita R DuttaRoy, S Sharma, P Vijayachari, VK Kataria, SC Seghal
January 2009, 129(1):105-107
PMID:19287068
Full text not available  [PDF]  [PubMed]
  105 92 -
ORIGINAL ARTICLES
Systemic manifestations in chronic arsenic toxicity in absence of skin lesions in West Bengal
KK Majumdar, DN Guha Mazumder, N Ghose, A Ghose, S Lahiri
January 2009, 129(1):75-82
PMID:19287062
Full text not available  [PDF]  [PubMed]
  79 117 -
COMMENTARIES
Ectopic Cushing's syndrome : some facts
R Salvatori
January 2009, 129(1):4-6
PMID:19287051
Full text not available  [PDF]  [PubMed]
  81 112 -
ORIGINAL ARTICLES
Murine monoclonal anti-H as typing reagent
YS Iyer, K Vasantha, V Pujari, S Jadhav, K Ghosh
January 2009, 129(1):72-74
PMID:19287061
Full text not available  [PDF]  [PubMed]
  98 93 -
COMMENTARIES
Challenges in providing HIV care to paediatric age group in India
P Haldar, DC S Reddy
January 2009, 129(1):7-10
PMID:19287052
Full text not available  [PDF]  [PubMed]
  98 91 -
BOOK REVIEWS
Monitoring and evaluation of mental health policies and plans
Shridhar Sharma
January 2009, 129(1):111-112
Full text not available  [PDF]
  91 75 -
ORIGINAL ARTICLES
Endothelial nitric oxide synthase (eNOS) Glu298-->Asp polymorphism (G894T) among south Indians
NS Nishevitha, T Angeline, N Jeyaraj
January 2009, 129(1):68-71
PMID:19287060
Full text not available  [PDF]  [PubMed]
  77 89 -
SOME FORTHCOMING SCIENTIFIC EVENTS
Some Forthcoming Scientific Events

January 2009, 129(1):115-115
Full text not available  [PDF]
  65 87 -
BOOK REVIEWS
Evaluation of certain food additives and contaminants
Kalpgam Polasa
January 2009, 129(1):112-114
Full text not available  [PDF]
  71 72 -
BOOK RECEIVED
Book Received

January 2009, 129(1):114-114
Full text not available  [PDF]
  63 62 -
ORIGINAL ARTICLES
Expression of class III β-tubulin in colorectal carcinomas : an immunohistochemical study using TU-20 & TuJ-1 antibody.
T Jirásek, Š Cipro, A Musilová, M Kubecová, V Mandys
January 2009, 129(1):89-94
PMID:19287064
Full text not available  [PDF]  [PubMed]
  51 65 -
ANNOUNCEMENT
Announcement

January 2009, 129(1):115-115
Full text not available  [PDF]
  0 0 -
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