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August 2007 Volume 126 | Issue 2
Page Nos. 91-170
Online since Friday, May 20, 2011
Accessed 6,633 times.
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EDITORIALS |
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Polio eradication & India--bringing science into public health |
p. 91 |
T Jacob John PMID:17932428 |
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The current status of international standards for child growth |
p. 94 |
N Bhandari, M de Onis PMID:17932429 |
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COMMENTARIES |
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Outcome of critically ill HIV infected patients--a huge need for early screening |
p. 97 |
JF Timsit PMID:17932430 |
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Identifying human cytomegalovirus genotypes & defining their clinical significance |
p. 99 |
L Dar PMID:17932431 |
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Spotted fevers & typhus fever in Tamil Nadu  |
p. 101 |
HV Batra PMID:17932432 |
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REVIEW ARTICLES |
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The role of epigenetics in mental disorders |
p. 105 |
J Peedicayil PMID:17932433It is well established that the idiopathic mental disorders have a genetic basis. Yet, genetic mapping has not definitively identified any genetic mutation or polymorphism underlying these disorders. This review discusses the role of epigenetics in the pathogenesis of the idiopathic mental disorders. Epimutations and epigenetic polymorphisms are emphasized as being an interface between the genes underlying the idiopathic mental disorders and the environment. Psychosocial factors are described as important environmental factors involved in the pathogenesis of the idiopathic mental disorders, modifying the underlying genes by epigenetic mechanisms. Epigenetic strategies to identify the genes underlying the idiopathic mental disorders are described and the available molecular evidence supporting an epigenetic pathogenesis for these disorders is discussed. It also discusses the role of epigenetic factors in the pathogenesis of neuropsychiatric disorders and the relevance of the new therapeutic option, epigenetic therapy, in treating the idiopathic mental disorders and the neuropsychiatric disorders. |
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Laboratory-based dengue fever surveillance in Tamil Nadu, India |
p. 112 |
T John Victor, M Malathi, R Asokan, P Padmanaban PMID:17932434Dengue fever and dengue haemorrhagic fever (DF/DHF) have become a serious public health problem in many parts of India in recent years. Several vertical national programmes for communicable diseases, which include vector-borne diseases such as malaria and filariasis have been in operation for over five decades in India. The remarkable increase in dengue fever and DHF related deaths during the last decade has necessitated an effective surveillance system to detect the cases and adopt appropriate control measures against dengue vectors. Although the existence of all the four serotypes of dengue virus was proved as early as in 1960s, it was only after 1990, several outbreaks of DF/DHF were reported in Tamil Nadu. Further, dengue, once considered as urban problem has now penetrated into rural areas also, due to various changes in the environment. The geographic spread, increase in number of cases, reporting system, laboratory diagnosis, monitoring of vector density and investigation of outbreaks in Tamil Nadu during the last decade are comprehensively documented and discussed here to further strengthen the surveillance network to prevent possible major outbreaks of DF/DHF. |
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ORIGINAL ARTICLES |
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Mortality & clinical characteristics of hospitalized adult patients with HIV in Pune, India |
p. 116 |
R Sobhani, A Basavaraj, A Gupta, Ashok S Bhave, Dilip B Kadam, Shashikala A Sangle, Haridas B Prasad, J Choi, J Josephs, Kelly A Gebo, Shweta N Morde, Robert C Bollinger, Arjun L Kakrani PMID:17932435 |
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Comparative efficacy of PCR-based restriction fragment length polymorphism (RFLP) & multiplex PCR for glycoprotein B (gB) genotyping of human cytomegalovirus |
p. 122 |
P Sowmya, V Dhanya, HN Madhavan, KL Therese PMID:17932436 |
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Serological evidence for wide distribution of spotted fevers & typhus fever in Tamil Nadu |
p. 128 |
K Kamarasu, M Malathi, V Rajagopal, K Subramani, D Jagadeeshramasamy, E Mathai PMID:17932437 |
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Mother-to-child transmission of HIV among women who chose not to exclusively breastfeed their infants in Pune, India |
p. 131 |
A Gupta, N Gupte, J Sastry, Kapila E Bharucha, R Bhosale, P Kulkarni, S Tripathy, U Nayak, M Phadke, Robert C Bollinger PMID:17932438 |
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Interleukin-12B & interleukin-10 gene polymorphisms in pulmonary tuberculosis |
p. 135 |
S Prabhu Anand, P Selvaraj, MS Jawahar, AR Adhilakshmi, PR Narayanan PMID:17932439 |
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Effect of platelet-activating factor on cell proliferation & NF-kappaB activation in airway smooth muscle cells in rats |
p. 139 |
S Ying-fang, H Jing-fang, L Huan-zhang, Q Hao-wen PMID:17932440 |
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Pulsed field gel electrophoresis & plasmid profile of Pseudomonas aeruginosa at two hospitals in Tehran, Iran |
p. 146 |
VS Nikbin, A Abdi-Ali, MM Feizabadi, S Gharavi PMID:17932441 |
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Ecological study on mosquito vectors of Japanese encephalitis virus in Bellary district, Karnataka |
p. 152 |
PC Kanojia PMID:17932442 |
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CORRESPONDENCES |
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Counselling needs of persons exposed to human immunodeficiency virus |
p. 158 |
G Alexander, BJ Sunitha, LK Chitra, PS Rao PMID:17932443 |
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New multilocus sequence types of Streptococcus pneumoniae isolates from patients with respiratory infections in India |
p. 161 |
M Shariff, SS Thukral, B Beall PMID:17932444 |
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BOOK REVIEWS |
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Disease control priorities, related to mental, neurological, developmental and substance abuse disorders |
p. 165 |
Shridhar Sharma |
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Evaluation of certain veterinary drug residues in food |
p. 166 |
Kalpgam Polasa |
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Modern trends in planning and designing of hospitals: Principles and practice  |
p. 167 |
AK Gupta |
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SOME FORTHCOMING SCIENTIFIC EVENTS |
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Some forthcoming scientific events |
p. 169 |
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