Indian Journal of Medical Research

CORRESPONDENCE
Year
: 2019  |  Volume : 150  |  Issue : 4  |  Page : 417--418

Authors' response


Sharmili Sinha1, Suneeta Sahu2, Jyotirmaya Pati1, Banambar Ray1, Saroj Kumar Pattnaik1,  
1 Department of Critical Care Medicine, Apollo Hospitals, Bhubaneswar 751 005, Odisha, India
2 Department of Microbiology, Apollo Hospitals, Bhubaneswar 751 005, Odisha, India

Correspondence Address:
Sharmili Sinha
Department of Critical Care Medicine, Apollo Hospitals, Bhubaneswar 751 005, Odisha
India




How to cite this article:
Sinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Authors' response.Indian J Med Res 2019;150:417-418


How to cite this URL:
Sinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Authors' response. Indian J Med Res [serial online] 2019 [cited 2021 Sep 23 ];150:417-418
Available from: https://www.ijmr.org.in/text.asp?2019/150/4/417/272085


Full Text

We thank the author[1] for her interest in our study[2].

The authors have mentioned about the definition of a pandrug-resistant (PDR) isolate as described by Ghafur et al[3]. This implies that the criteria have been followed to brand the organism as a PDR.It is agreed that the CLSI/EUCAST-approved micro broth dilution remains a challenge till date in routine microbiology laboratories. Hence, this is not being used in our laboratory which is a routine laboratory only. Instead, the available and accessible methods are used. Hence, susceptibility to colistin has been determined by E-strip as well as correlating it with VITEK-2 minimum inhibitory concentration reports. We are aware that both these methods can have major errors. Therefore, it has been stated that colistin susceptibility has to be interpreted with caution and treatment should be done only after judicious clinical assessment. The isolates were judged as pathogen or colonizer by two independent assessors before being actually treated.

References

1Behara B. Challenges & issues of colistin susceptibility testing in diagnostic microbiology laboratories. Indian J Med Res 2019; 150 : 417-8.
2Sinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India. Indian J Med Res 2019; 149 : 418-22.
3Ghafur A, Vidyalakshmi PR, Murali A, Priyadarshini K, Thirunarayan MA. Emergence of pan-drug resistance amongst Gram-negative bacteria1. The first case series from India. J Microbial Infect Disease 2014; 4 : 86-91.