Indian Journal of Medical Research

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 149  |  Issue : 3  |  Page : 418--422

Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India


Sharmili Sinha1, Suneeta Sahu2, Jyotirmaya Pati1, Banambar Ray1, Saroj Kumar Pattnaik1 
1 Department of Critical Care Medicine, Apollo Hospitals, Bhubaneswar, India
2 Department of Microbiology, Apollo Hospitals, Bhubaneswar, India

Correspondence Address:
Dr Sharmili Sinha
Department of Critical Care Medicine, Apollo Hospitals, Old Sainik School Road, Samantapuri, Bhubaneswar 751 005, Odisha
India

The incidence of carbapenem-resistant Enterobacteriaceae has been steadily rising. The morbidity, mortality and financial implications of such patients are significant. We did a retrospective analysis of the case records of 11 patients who had culture report positive for pan drug-resistant (PDR) organisms. There were total 15 isolates of PDR organisms in 11 patients. These were associated with catheter-associated urinary tract infections (7), tracheitis (4), bacteraemia (2), meningitis (1) and soft-tissue infection (1). Average APACHE II score was 23.72 (range 7-36) indicating patients with multiple co-morbidities and organ dysfunction. The average length of hospital stay was 60.72 (25-123) days. The overall mortality rate was 81.81 per cent, while PDR infection-related mortality was 18.18 per cent. Strict implementation of antibiotic stewardship programme is essential to limit use and prevent abuse of colistin.


How to cite this article:
Sinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India.Indian J Med Res 2019;149:418-422


How to cite this URL:
Sinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India. Indian J Med Res [serial online] 2019 [cited 2020 Nov 28 ];149:418-422
Available from: https://www.ijmr.org.in/article.asp?issn=0971-5916;year=2019;volume=149;issue=3;spage=418;epage=422;aulast=Sinha;type=0