Indian Journal of Medical Research

REVIEW ARTICLE
Year
: 2008  |  Volume : 128  |  Issue : 4  |  Page : 524--532

The interpretation of trace element analysis in body fluids


TL Guidotti, J McNamara, MS Moses 
 Department of Environmental & Occupational Health, School of Public Health & Health Services, George Washington University, Washington, DC 20052, USA

Correspondence Address:
T L Guidotti
Department of Environmental & Occupational Health, School of Public Health & Health Services, George Washington University, Washington, DC 20052, USA

The clinical interpretation of trace element analysis has lagged behind the technology available to measure the elements in body fluids. Reports can be difficult to interpret and requires knowledge of toxicokinetics, the dynamics of how the trace metals accumulate and pass through the body. Trace element analysis is best used for specific applications, such as establishing levels of exposure, biological exposure indices, biomonitoring of populations, and to confirm an association following a compatible diagnosis. It is not well suited for screening individual patients. Chelation treatment may follow inappropriate trace element determinations and may carry a risk of side effects, some life-threatening. Trace element analysis should be used sparingly and with full understanding of what the results are likely to mean. The physician should only order the test with a clear idea of why he or she is doing so and what he or she will do with the result.


How to cite this article:
Guidotti T L, McNamara J, Moses M S. The interpretation of trace element analysis in body fluids.Indian J Med Res 2008;128:524-532


How to cite this URL:
Guidotti T L, McNamara J, Moses M S. The interpretation of trace element analysis in body fluids. Indian J Med Res [serial online] 2008 [cited 2021 Jan 19 ];128:524-532
Available from: https://www.ijmr.org.in/article.asp?issn=0971-5916;year=2008;volume=128;issue=4;spage=524;epage=532;aulast=Guidotti;type=0