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ORIGINAL ARTICLE
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Demographic & clinical profile of patients with COVID-19 at a tertiary care hospital in north India


1 Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India
2 Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India
3 Department of Virology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
4 Department of Pulmonary Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India
5 Department of Hospital Administration, Postgraduate Institute of Medical Education & Research, Chandigarh, India
6 Department of Pathology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
7 Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
8 Department of Community Medicine & School of Public Health, Postgraduate Institute of Medical Education & Research, Chandigarh, India
9 Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh, India
10 Department of Pediatrics, Postgraduate Institute of Medical Education & Research, Chandigar, India
11 Department of Hematology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
12 Department of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India

Correspondence Address:
Vikas Suri,
Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh 160 012
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijmr.IJMR_2311_20

PMID: 33208558

Background & objectives: The COVID-19 pandemic emerged as a major public health emergency affecting the healthcare services all over the world. It is essential to analyze the epidemiological and clinical characteristics of patients with COVID-19 in different parts of our country. This study highlights clinical experience in managing patients with COVID-19 at a tertiary care centre in northern India. Methods: Clinical characteristics and outcomes of consecutive adults patients admitted to a tertiary care hospital at Chandigarh, India, from April 1 to May 25, 2020 were studied. The diagnosis of SARS-CoV-2 infection was confirmed by real-time reverse transcriptase polymerase chain reaction (RT-PCR) on throat and/or nasopharyngeal swabs. All patients were managed according to the institute's consensus protocol and in accordance with Indian Council of Medical Research guidelines. Results: During the study period, 114 patients with SARS-CoV-2 infection were admitted. The history of contact with COVID-19-affected individuals was available in 75 (65.8%) patients. The median age of the patients was 33.5 yr (13-79 yr), and there were 66 (58%) males. Of the total enrolled patients, 48 (42%) were symptomatic. The common presenting complaints were fever (37, 77%), cough (26, 54%) and shortness of breath (10, 20.8%). Nineteen (17%) patients had hypoxia (SpO2<94%) at presentation and 36 (31%) had tachypnoea (RR >24). Thirty four (29.8%) patients had an accompanying comorbid illness. Age more than 60 yr and presence of diabetes and hypertension were significantly associated with severe COVID-19 disease. Admission to the intensive care unit (ICU) was needed in 18 patients (52%), with three (2.6%) patients requiring assisted ventilation. Mortality of 2.6 per cent (3 patients) was observed. Interpretation & conclusions: Majority of the patients with COVID-19 infection presenting to our hospital were young and asymptomatic. Fever was noted only in three-fourth of the patients and respiratory symptoms in half of them. Patients with comorbidities were more vulnerable to complications. Triaged classification of patients and protocol-based treatment resulted in good outcomes and low case fatality.


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