Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research
  Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login  
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 912       

   Table of Contents      
CLINICAL IMAGE
Year : 2020  |  Volume : 152  |  Issue : 7  |  Page : 44

Recalcitrant periungual warts in a paediatric patient treated with intralesional vitamin D3


Department of Dermatology, Venereology & Leprosy, Government Medical College, Kota 324 010, Rajasthan, India

Date of Submission09-Oct-2019
Date of Web Publication25-May-2021

Correspondence Address:
Suresh Kumar Jain
Department of Dermatology, Venereology & Leprosy, Government Medical College, Kota 324 010, Rajasthan
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmr.IJMR_1737_19

Rights and Permissions

How to cite this article:
Mohta A, Jain SK. Recalcitrant periungual warts in a paediatric patient treated with intralesional vitamin D3. Indian J Med Res 2020;152, Suppl S1:44

How to cite this URL:
Mohta A, Jain SK. Recalcitrant periungual warts in a paediatric patient treated with intralesional vitamin D3. Indian J Med Res [serial online] 2020 [cited 2021 Jul 31];152, Suppl S1:44. Available from: https://www.ijmr.org.in/text.asp?2020/152/7/44/316727

Consent to publish clinical information and images obtained from patient's father.


A seven year male child presented to the outpatient department of Dermatology, Venereology & Leprosy, Government Medical College, Kota, Rajasthan, India, in March 2019, with multiple painful verrucous lesions over the tip of the right great toe for the last one year, involving the adjacent hyponychium and nail bed [Figure 1]A. The patient was diagnosed with periungual warts. Before presentation, topical agents such as 100 trichloroacetic acid, salicylic acid and radiofrequency ablation had been tried followed by repeated recurrences and progressive increase in size. After confirming the patient's immunocompetent status, 0.2 ml of intralesional injections of vitamin D3 (15 mg/ml) was given at the base of the warts, after injecting local anaesthetic. Injections were repeated at three “weeks” intervals with monitoring of serum calcium level at every visit. The lesions started resolving after the second dose [Figure 1]B, and complete clearance was observed four weeks after the third injection, with the resolution of skin markings [Figure 1]C. Monthly follow up was done for the next three months with no recurrence.
Figure 1: (A) Periungual warts over right great toe (baseline). (B) Serial improvement following second dose of vitamin D3. (C) Complete resolution with reappearance of skin markings four weeks after the third injection.

Click here to view


Immunotherapy has emerged as an effective and safe modality for the treatment of recalcitrant or multiple warts. Unlike other immunotherapies (such as BCG or MMR) intralesional vitamin D3 has no adverse effects such as febrile illness or abscess formation and is, therefore, considered a safe option in paediatric patients.

Conflicts of Interest: None.


    Figures

  [Figure 1]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
    Article Figures

 Article Access Statistics
    Viewed144    
    Printed0    
    Emailed0    
    PDF Downloaded25    
    Comments [Add]    

Recommend this journal