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POLICY DOCUMENT
Year : 2020  |  Volume : 152  |  Issue : 5  |  Page : 468-474

Indian Council of Medical Research consensus document on hepatocellular carcinoma


1 Department of Medical Oncology, Apollo Proton Cancer Centre, Chennai, India
2 Department of Gastrointestinal & Hepato-Pancreato-biliary Service, Tata Memorial Centre, Mumbai, Maharashtra, India
3 Department of Gastrointestinal & Hepato-Pancreato-biliary Service, Paras Hospital, Gurugram, Haryana &, India
4 Department of Medical Oncology, Army Hospital Research & Referral, New Delhi, India
5 Department of Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India
6 Department of Medical Oncology, Dr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
7 Department of Radiation Oncology, Tata Medical Centre, Kolkata, West Bengal, India
8 Department of Gastroenterology, Institute of Liver & Biliary Sciences, New Delhi, India
9 Department of Interventional Radiology, Tata Memorial Centre, Mumbai, Maharashtra, India
10 Department of Radiodiagnosis, Dr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
11 Division of Non-Communicable Diseases, Indian Council of Medical Research, New Delhi, India
12 Department of Radiation Oncology, Dr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Bhawna Sirohi
Department of Medical Oncology, Apollo Proton Cancer Centre, Chennai 600 028, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmr.IJMR_404_20

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This document aims to assist oncologists in making clinical decisions encountered while managing their patients with hepatocellular carcinoma (HCC), specific to Indian practice, based on consensus among experts. Most patients are staged by Barcelona Clinic Liver Cancer (BCLC) staging system which comprises patient performance status, Child-Pugh status, number and size of nodules, portal vein invasion and metastasis. Patients should receive multidisciplinary care. Surgical resection and transplant forms the mainstay of curative treatment. Ablative techniques are used for small tumours (<3 cm) in patients who are not candidates for surgical resection (Child B and C). Patients with advanced (HCC should be assessed on an individual basis to determine whether targeted therapy, interventional radiology procedures or best supportive care should be provided. In advanced HCC, immunotherapy, newer targeted therapies and modern radiation therapy have shown promising results. Patients should be offered regular surveillance after completion of curative resection or treatment of advanced disease.


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