Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research
  Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login  
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 14283       

   Table of Contents      
CLINICAL IMAGE
Year : 2020  |  Volume : 152  |  Issue : 4  |  Page : 432-433

Extensive palpebral molluscum contagiosum in an immunocompetent child


Department of Ophthalmology, Lady Hardinge Medical College, New Delhi 110 001, India

Date of Submission31-Mar-2019
Date of Web Publication28-Dec-2020

Correspondence Address:
Dr. Om Prakash
Department of Ophthalmology, Lady Hardinge Medical College, New Delhi 110 001
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmr.IJMR_584_19

Rights and Permissions

How to cite this article:
Prakash O, Sethi M. Extensive palpebral molluscum contagiosum in an immunocompetent child. Indian J Med Res 2020;152:432-3

How to cite this URL:
Prakash O, Sethi M. Extensive palpebral molluscum contagiosum in an immunocompetent child. Indian J Med Res [serial online] 2020 [cited 2021 Jan 18];152:432-3. Available from: https://www.ijmr.org.in/text.asp?2020/152/4/432/305167

Consent to publish clinical information and images obtained from patient's father.


A seven year old boy was brought to the Ophthalmology department at Lady Hardinge Medical College, New Delhi, India, in August 2017 with a six-month history of progressively enlarging raised lesions on his right upper and lower eyelids. On examination, he had three pitted globular lesions with central umbilication on the right upper eyelid and a similar lesion on the lower lid [Figure 1] with the largest one being 9 mm × 8 mm × 6 mm with overlying prominent dilated vessel. Similar lesions were noted in the right nostril, the angle of mouth and ala of nose of the same side [Figure 2]. Complete blood count and immunoglobulin levels were normal. Serological tests for HIV and hepatitis A, B and C viruses were negative. CD4 count was not done. There was no history of the use of systemic steroids. Meticulous extirpation of the lesions was done along with cauterization of the base with trichloroacetic acid, with a good cosmetic outcome [Figure 3]. Histopathology showed intracytoplasmic eosinophilic inclusions (Henderson-Paterson bodies) within the keratinocytes of the basal, spinous and granular layers of epidermis, compressing the nucleus to periphery [Figure 4], confirming molluscum contagiosum. No recurrence was noted at follow up after two months.
Figure 1: Pitted globular lesions with central umbilication on the right upper and lower eyelid with overlying prominent dilated blood vessel.

Click here to view
Figure 2: Umbilicated lesions in the right nostril, angle of mouth and ala of nose.

Click here to view
Figure 3: Results after extirpation of the lesions along with cauterization of the base with trichloroacetic acid.

Click here to view
Figure 4: Photomicrograph of the excised lesions showing intracytoplasmic eosinophilic inclusions (yellow arrows represent Henderson-Paterson bodies) within the keratinocytes, compressing the nucleus to periphery confirming molluscum contagiosum (H and E, ×40).

Click here to view


Molluscum contagiosum, a chronic infection caused by poxvirus in immunocompromised patients, is characterized by multiple centrally umbilicated papules. Treatment options include extirpation, cryotherapy, cauterization and topical cidofovir (5%) or imiquimod (5%) cream.

Acknowledgment: Authors thank Dr Kiran Agarwal, Department of Pathology, Lady Hardinge Medical College, New Delhi, for kindly providing histopathology images and their interpretation that greatly improved the manuscript.

Conflicts of Interest: None.


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
    Article Figures

 Article Access Statistics
    Viewed204    
    Printed2    
    Emailed0    
    PDF Downloaded93    
    Comments [Add]    

Recommend this journal