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Year : 2012  |  Volume : 135  |  Issue : 5  |  Page : 796-797

Principles of perinatal and pediatric HIV/AIDS

Child Development Centre, Medical College campus, Thiruvananthapuram 695 011, India

Date of Web Publication29-Jun-2012

Correspondence Address:
M.K.C. Nair
Child Development Centre, Medical College campus, Thiruvananthapuram 695 011
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Source of Support: None, Conflict of Interest: None

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How to cite this article:
Nair M. Principles of perinatal and pediatric HIV/AIDS. Indian J Med Res 2012;135:796-7

How to cite this URL:
Nair M. Principles of perinatal and pediatric HIV/AIDS. Indian J Med Res [serial online] 2012 [cited 2021 Jun 13];135:796-7. Available from:

M.M. Lala, R.H. Merchant, editors [Jaypee Brothers Medical Publishers (P) Ltd., New Delhi]. 2012. Pages 627. Price: not mentioned.

ISBN 978-93-5025-197-3

This book provides an impressive and elaborate coverage of perinatal and paediatric HIV infections, and draws attention to an area which is globally important but has not gained the required attention i.e. the pandemic of paediatric HIV infection. This textbook should meet the requirements of most of the caregivers who are working in this field and will guide them in their daily management of this dreadful disease.

This book is a contribution by two eminent physicians who have dedicated number of years in this field. Moreover, valuable contributions have been made by several national and international authorities belonging to various centres of excellence in Africa, US and Europe, making this book a treasure house of knowledge.

The book has a total of 47 chapters divided under six sections covering in detail all spheres of this infective disease right from immunology, virology, natural history, diagnostic modalities and difficulties in management. Children, as they have poorly developed immunity, have greater dissemination of infection through various organs giving rise to varied clinical manifestations. In children with AIDS, occurrence of malignancies, immune reconstitution inflammatory syndrome, opportunistic infections, co-infection with tuberculosis, hepatitis B, hepatitis C, and Malaria with HIV have all been included. It impresses the dangers of vertical transmission of HIV, prevention of mother-to-child transmission and safety and efficacy of anti-retroviral therapy (ART). Guidelines regarding breast feeding, care of newborn have also been given. In this era with better treatment options and survival of perinatally infected children into adolescence, HIV and its effects on growth, development and puberty have been delicately handled. Issues pertaining to nutrition, immunization, drug resistance, professional, ethical and legal issues all have been covered elaborately.

India carries a huge burden of HIV, next only to South Africa and Nigeria. The National AIDS Control Organization (NACO) estimates show that 70,000 children below the age of 15 yr are infected with HIV in India and 21,000 develop infection every year through mother to child transmission. The greatest milestone in this area has been the ability to interrupt this transmission through anti-retroviral therapy, and the second one is the effect on morbidity and mortality of perinataly infected infants due to early detection and treatment.

This wealth of knowledge will definitely come a long way in scaling down the suffering of those afflicted and improve the quality of care that they receive. It would be extremely useful for all health care providers involved in the management of perinatal HIV prevention and paediatric AIDS, and also for students.


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