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  Indian J Med Microbiol
 

Figure 2: A collage of histopathological findings in allergic bronchopulmonary aspergillosis. Gross photograph showing cystically dilated bronchi and bronchioles and lumen filled with brownish mucous plugs (panel 1A). Photomicrograph showing dilated bronchial lumen filled with allergic mucin (panel 1B; H and E, ×40). Low-power photomicrograph of allergic mucin having variegated appearance, containing mucin admixed with eosinophils, eosinophilic debris and other inflammatory cells arranged in a laminar pattern (panel 2; H and E, ×100). High-power photomicrograph of allergic mucin containing mucin admixed with eosinophils, Charcot laden crystals (thick arrow) and a few septate fungal hyphae (thin arrow) (panel 3; H and E, ×400). Photomicrographs of periodic acid-Schiff stain (panel 4A, ×400) and Grocott's stain (panel 4B, ×400) highlighting scattered fungal hyphae (arrows) within allergic mucin. Photomicrograph showing alveolar spaces filled with eosinophils indicative of eosinophilic pneumonia (panel 5; H and E, ×200). Photomicrograph of bronchocentric granulomatosis (panel 6) with occasional multinucleate giant cell (black arrow).

Figure 2: A collage of histopathological findings in allergic bronchopulmonary aspergillosis. Gross photograph showing cystically dilated bronchi and bronchioles and lumen filled with brownish mucous plugs (panel 1A). Photomicrograph showing dilated bronchial lumen filled with allergic mucin (panel 1B; H and E, ×40). Low-power photomicrograph of allergic mucin having variegated appearance, containing mucin admixed with eosinophils, eosinophilic debris and other inflammatory cells arranged in a laminar pattern (panel 2; H and E, ×100). High-power photomicrograph of allergic mucin containing mucin admixed with eosinophils, Charcot laden crystals (thick arrow) and a few septate fungal hyphae (thin arrow) (panel 3; H and E, ×400). Photomicrographs of periodic acid-Schiff stain (panel 4A, ×400) and Grocott's stain (panel 4B, ×400) highlighting scattered fungal hyphae (arrows) within allergic mucin. Photomicrograph showing alveolar spaces filled with eosinophils indicative of eosinophilic pneumonia (panel 5; H and E, ×200). Photomicrograph of bronchocentric granulomatosis (panel 6) with occasional multinucleate giant cell (black arrow).