Figure 6: Expression of cyclin E on prostate tissue detected by immunohistochemistry (magnification ×200) of cyclin E protein. The IOD of DAB stain taken by cyclin E protein shows a significant increase of cyclin E expression in carcinogenic and non-carcinogenic (benign) tumours. Increased expression was observed in the carcinoma prostate group. Arrows indicate areas of higher expression. Each bar shows the mean±standard deviation of 25 samples. P**<0.01, ***<0.001 compared to sham control.