Close
  Indian J Med Microbiol
 

Figure 3: Extracellular levels of cytokines, (A) IFN-γ, (B) IL-17, (C) IL-23, (D) IL-10, (E) IL-4 and (F) IL-6 in culture supernatants of peripheral blood mononuclear cell (PBMC) cultures in type-1 diabetes mellitus (T1DM), LADA and healthy control (HC) groups after in vitro stimulation with insulin. Values are shown as mean±standard error of mean. Levels of secreted interleukin-17 (P=0.02) and interleukin-10 (P=0.01) were significantly higher in LADA group than T1DM group post insulin stimulation. PBMCs of HC group secreted very low levels of IL-6 that could not be observed on the depicted scale.

Figure 3: Extracellular levels of cytokines, (<b>A</b>) IFN-γ, (<b>B</b>) IL-17, (<b>C</b>) IL-23, (<b>D</b>) IL-10, (<b>E</b>) IL-4 and (<b>F</b>) IL-6 in culture supernatants of peripheral blood mononuclear cell (PBMC) cultures in type-1 diabetes mellitus (T1DM), LADA and healthy control (HC) groups after <i>in vitro</i> stimulation with insulin. Values are shown as mean±standard error of mean. Levels of secreted interleukin-17 (<i>P</i>=0.02) and interleukin-10 (<i>P</i>=0.01) were significantly higher in LADA group than T1DM group post insulin stimulation. PBMCs of HC group secreted very low levels of IL-6 that could not be observed on the depicted scale.