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  Indian J Med Microbiol
 

Figure 2: Percentage of individuals secreting various cytokines following in vitro stimulation of peripheral blood mononuclear cells. (A) Post-insulin stimulation, latent autoimmune diabetes in adults (LADA) group showed significantly higher number of responders secreting interferon gamma (IFN-γ) and interleukin-10 (IL-10). (B) Post-glutamic acid decarboxylase 65 (GAD-65) stimulation, LADA group showed significantly higher responders secreting IL-23 and IL-10. Interleukin-6 secretion was compared only in case of insulin stimulation. Responders were defined as those secreting detectable cytokine levels at the end of incubation period, as compared to zero hour.

Figure 2: Percentage of individuals secreting various cytokines following <i>in vitro</i> stimulation of peripheral blood mononuclear cells. (<b>A</b>) Post-insulin stimulation, latent autoimmune diabetes in adults (LADA) group showed significantly higher number of responders secreting interferon gamma (IFN-γ) and interleukin-10 (IL-10). (<b>B</b>) Post-glutamic acid decarboxylase 65 (GAD-65) stimulation, LADA group showed significantly higher responders secreting IL-23 and IL-10. Interleukin-6 secretion was compared only in case of insulin stimulation. Responders were defined as those secreting detectable cytokine levels at the end of incubation period, as compared to zero hour.