Figure 1: Adipose tissue histology in four month old, male WNIN/Ob lean and obese rats. (A) Photographs of H&E stained retroperitoneal adipose tissue to study adipocyte size and inflammation. ‘L’ indicates lean sample and ‘O’ indicates obese sample. Arrow marks indicate the presence of infiltrated inflammatory cells. (B) Adipocyte size calculated as a number of cells/16 mm2 (n=4/phenotype). *** indicates P< 0.001 compared to lean rats.