Figure 2. Reduced effector cytokine production in SMAR1 Tg. mice during DSS colitis. Quantification of ex vivo production of IL-6 (A) , IFN γ (B) , IL-17 (C) and IL-12 (D) by purified intraepithelial lymphocytes from untreated (U) and DSS treated (T) colons. Data represent the mean ±SEM (n=6). Unpaired student t test was used for statistical analysis. P*<0.05, **<0.001 compared with WT.