Indian Journal of Medical Research

BOOK REVIEW
Year
: 2012  |  Volume : 136  |  Issue : 6  |  Page : 1064-

Nanomedicine - Basic and clinical applications in diagnostics and therapy


Sanjeeb K Sahoo 
 Nanomedicine Laboratory, Institute of Life Sciences Nalco Square, Chandrasekharpur, Bhubaneswar 751 023, India

Correspondence Address:
Sanjeeb K Sahoo
Nanomedicine Laboratory, Institute of Life Sciences Nalco Square, Chandrasekharpur, Bhubaneswar 751 023
India




How to cite this article:
Sahoo SK. Nanomedicine - Basic and clinical applications in diagnostics and therapy.Indian J Med Res 2012;136:1064-1064


How to cite this URL:
Sahoo SK. Nanomedicine - Basic and clinical applications in diagnostics and therapy. Indian J Med Res [serial online] 2012 [cited 2019 Jul 24 ];136:1064-1064
Available from: http://www.ijmr.org.in/text.asp?2012/136/6/1064/106943


Full Text

Nanomedicine - Basic and clinical applications in diagnostics and therapy , C. Alexiou, editor (S. Kargar, Basel, Switzerland). 2011. 202 pages.

ISBN 978-3-8055-9818-7

This is a multi-authored state of art compendium about the significant advances in the field of nanotechnology offering new tools, opportunities and scope which are expected to have a great impact on many areas in disease diagnostics and therapeutics. The book series in essence features the Proceedings of the 2 nd Else Kroner - Fresenius Symposium and the title of the book and the contents clearly showcase the concept that nanotechnology has emerged as a discipline having enormous potential as carrier for spatial and temporal delivery of bioactives and diagnostics, and provides smart materials for therapeutic purpose. The book is divided into discrete chapters rationally grouped into six sections (the 1 st section being about the authors at the symposium) where each section is written by authors proficient in their fields of study. Each section highlights one facet of nanotechnology and the individual topics under each section have been dealt with in a lucid way.

The introductory chapter summarizes the use of materials in nanoscale which provides unparallel freedom to modify fundamental properties of materials such as solubility, diffusivity, blood circulation half-life, drug release characteristics, and immunogenicity resulting in formulation of nanoparticles. The snapshots of recent research in nano drug-delivery systems provided in the section entitled "Nano scale drug delivery/ drug design" prove that personalized health care, rational drug design, and targeted drug delivery are some of the benefits of a nanomedicine-based approach to therapy.

There are several confounding unresolved issues, which warrant the application of nanotechnology in its full bloom. Some concerning issues like safety, toxicity hazards, bioethical issues, physiological and nanotoxicity pharmaceutical challenges are yet to be resolved by the scientists. The section about toxicity deals with this issue in a comprehensive way hinting for further research on nanotoxicity.

The section entitled "Diagnostics and Imaging" is about the development of tumour-targeted contrast agents based on a nanoparticle formulation offering enhanced sensitivity and specificity for in vivo tumour imaging using currently available clinical imaging modalities. By applying a vast and diverse array of nanoparticles cancer nanotechnology promises solutions to several of the current obstacles facing cancer therapies. In fact, the article about "Cancer stem cells-new targets for diagnostics and therapy" is very lucrative and paves way for the development of platform for targeted theranostics.

In the past two decades, there has been a progressive increase in the number of commercially available nanoparticle-based therapeutic products. The medical application of nanoparticles is gaining popularity. In this milieu, the segment about "Therapeutic application" of nanoformulation gives an overview about the increasing momentum in the pace of discovery about the therapeutic implications of nanoparticles for a myriad of clinical indications particularly cancer. The subject of "Antibody therapy" highlights another modality which can be exploited for cancer therapy in near future.

Overall, the book series is highly specialized but easily comprehensible. The meticulous representation of facts makes the book highly resourceful and is recommended for all researchers both clinical and non clinical working in the field of nanotechnology.