|Year : 2019 | Volume
| Issue : 4 | Page : 417-418
Sharmili Sinha1, Suneeta Sahu2, Jyotirmaya Pati1, Banambar Ray1, Saroj Kumar Pattnaik1
1 Department of Critical Care Medicine, Apollo Hospitals, Bhubaneswar 751 005, Odisha, India
2 Department of Microbiology, Apollo Hospitals, Bhubaneswar 751 005, Odisha, India
|Date of Submission||28-Aug-2019|
|Date of Web Publication||29-Nov-2019|
Department of Critical Care Medicine, Apollo Hospitals, Bhubaneswar 751 005, Odisha
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Sinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Authors' response. Indian J Med Res 2019;150:417-8
We thank the author for her interest in our study.
- The authors have mentioned about the definition of a pandrug-resistant (PDR) isolate as described by Ghafur et al. This implies that the criteria have been followed to brand the organism as a PDR.
- It is agreed that the CLSI/EUCAST-approved micro broth dilution remains a challenge till date in routine microbiology laboratories. Hence, this is not being used in our laboratory which is a routine laboratory only. Instead, the available and accessible methods are used. Hence, susceptibility to colistin has been determined by E-strip as well as correlating it with VITEK-2 minimum inhibitory concentration reports. We are aware that both these methods can have major errors. Therefore, it has been stated that colistin susceptibility has to be interpreted with caution and treatment should be done only after judicious clinical assessment. The isolates were judged as pathogen or colonizer by two independent assessors before being actually treated.
| References|| |
Behara B. Challenges & issues of colistin susceptibility testing in diagnostic microbiology laboratories. Indian J Med Res
Sinha S, Sahu S, Pati J, Ray B, Pattnaik SK. Retrospective analysis of colistin-resistant bacteria in a tertiary care centre in India. Indian J Med Res
Ghafur A, Vidyalakshmi PR, Murali A, Priyadarshini K, Thirunarayan MA. Emergence of pan-drug resistance amongst Gram-negative bacteria1. The first case series from India. J Microbial Infect Disease