|Year : 2018 | Volume
| Issue : 4 | Page : 453-455
Detection of Kyasanur forest disease in newer areas of Sindhudurg district of Maharashtra State
Pragya D Yadav1, Rima R Sahay1, Devendra T Mourya2
1 Maximum Containment Laboratory, ICMR-National Institute of Virology, Pune 411 021, Maharashtra, India
2 ICMR-National Institute of Virology, Pune 411 021, Maharashtra, India
|Date of Submission||09-Aug-2017|
|Date of Web Publication||21-Jan-2019|
Devendra T Mourya
ICMR-National Institute of Virology, Pune 411 021, Maharashtra
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Yadav PD, Sahay RR, Mourya DT. Detection of Kyasanur forest disease in newer areas of Sindhudurg district of Maharashtra State. Indian J Med Res 2018;148:453-5
|How to cite this URL:|
Yadav PD, Sahay RR, Mourya DT. Detection of Kyasanur forest disease in newer areas of Sindhudurg district of Maharashtra State. Indian J Med Res [serial online] 2018 [cited 2020 May 26];148:453-5. Available from: http://www.ijmr.org.in/text.asp?2018/148/4/453/250527
Western Ghats of India is known for the presence of ideal climatic conditions for ticks. So far Kyasanur forest disease (KFD) hotspots have been detected in five States: Maharashtra, Goa, Kerala, Karnataka and Tamil Nadu. In Maharashtra State, this disease was first detected in Sindhudurg district in 2016. This district has eight talukas, namely, Deogad, Vaibhavwadi, Kankavli, Malwan, Kudal, Vengurla, Sawantwadi and Dodamarg. After first confirmation of KFD outbreak in the Dodamarg taluka (2016), there was confirmation of imported KFD cases from Sattari taluka Goa (among cashew-nut workers) to Belgaum (now Belagavi), and Banda area of Sawantwadi taluka where human, monkey autopsy and tick samples were positive.
The present communication reports detection of newer hot spots in Sindhudurg district in Maharashtra State: Kankavli, Kudal and Vengurla [Figure 1]. All the human serum/blood samples, monkey autopsy samples and tick pools referred from different talukas of Sindhudurg district to the National Institute of Virology, Pune, India, during 2015-2017 were included [Table 1]. The human samples were tested for the presence of KFD infection either by real-time reverse transcription polymerase chain reaction (RT-PCR) or by anti-KFD virus (KFDV) IgM ELISA. Tick pools and monkey necropsy samples were tested by real-time RT-PCR as defined earlier. This study emphasized on the presence of KFD activity in monkeys and ticks in other talukas of Sindhudurg such as Kankavli, Kudal and Vengurla where human positivity for KFD was not yet reported [Figure 1]. The data presented showed that either KFD was spreading in newer areas of Sindhudurg or it was already present [Table 1] and now identified due to increased awareness among people and public health authorities of Maharashtra State, India.
|Figure 1: Kyasanur forest disease virus activity in human, ticks and monkeys in different talukas of Sindhudurg district of Maharashtra State, India (2015-2016 & 2016-2017).|
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|Table 1: Kyasanur forest disease virus activity in human, ticks and monkeys in different talukas of Sindhudurg district of Maharashtra State, India|
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Sindhudurg district in Maharashtra has become a public health concern for this tick-borne disease. Movement of monkey and rodents play as an important contributor for the spread of KFD as they harbour infected ticks maintaining the transovarial and transstadial transmission,,,,,,,. Since 1920, rate of deforestation in the Western Ghats has been estimated to be 0.57 per cent annually. The deforestation and encroachment of local population for livestock activities helped in the transmission of this disease. The temperature and humidity of the area support the development of ticks as well as its survival, maintaining wildlife-livestock-human interfaces. The risk behaviours identified among KFDV cases in Sindhudurg were visiting to forest areas (for farming, collection of dry woods and leaves, cashew nut and coconut farming) for their livelihood.
Increase in magnitude of KFD disease in newer talukas of Sindhudurg calls for increase in active case surveillance and early case detection. There is also a need for preventive strategies such as KFD vaccination, health education regarding the spread of the KFD and use of tick repellent. The community should be educated to inform health authorities about monkey deaths, as it creates a hot zone for the presence of infected ticks. The morbidity and mortality prediction among animals can be an early sign for the detection of spread of the KFD in newer areas. There is a need for intersectoral coordination among forest authorities, animal husbandries, environmentalist, entomologist and public health system for future prediction of the disease spread, which is posing a public health challenge. Apart from vaccination, development of therapeutic antiviral drugs against KFD needs to be done.
Acknowledgment: Authors acknowledge the support rendered by Dr Pradeep Awate, State Epidemiologist, Dr Mahendra Jagtap, State Entomologist and Dr Mahesh Khalife, Additional Director of Health Services, Kolhapur district. Authors thank Dr Yogesh K. Gurav, Scientist 'D', National Institute of Virology, Pune and Shri Nikhilesh Pacharane, data entry operator, BSL-4 laboratory for support provided during the study.
Financial support & sponsorship: Financial supported was provided by GHSA-CDC grant no.6 NU2GGH001903-02-01, and the intramural funding was provided by the ICMR-NIV (Indian Council of Medical Research-National Institute of Virology), Pune.
Conflicts of Interest: None.
| References|| |
Holbrook MR. Kyasanur forest disease. Antiviral Res
Awate P, Yadav P, Patil D, Shete A, Kumar V, Kore P, et al.
Outbreak of Kyasanur forest disease (monkey fever) in Sindhudurg, Maharashtra State, India, 2016. J Infect
Patil DY, Yadav PD, Shete AM, Nuchina J, Meti R, Bhattad D, et al.
Occupational exposure of cashew nut workers to Kyasanur forest disease in Goa, India. Int J Infect Dis
Pattnaik P. Kyasanur forest disease: An epidemiological view in India. Rev Med Virol
Mourya DT, Yadav PD. Recent scenario of emergence of Kyasanur forest disease in India and public health importance. Curr Trop Med Rep
Banerjee K. Kyasanur forest disease. In: Monath TP, editor. Arboviruses epidemiology and ecology
. Boca Raton: CRC Press; 1988. p. 93-116.
Kasabi GS, Murhekar MV, Yadav PD, Raghunandan R, Kiran SK, Sandhya VK, et al.
Kyasanur forest disease, India, 2011-2012. Emerg Infect Dis
Mourya DT, Yadav PD, Sandhya VK, Reddy S. Spread of Kyasanur forest disease, Bandipur tiger reserve, India, 2012-2013. Emerg Infect Dis
Mourya DT, Yadav PD, Patil DY. Highly infectious tick borne viral diseases: Kyasanur forest disease and Crimean-Congo hemorrhagic fever in India. WHO South East Asia J Public Health
Yadav PD, Shete AM, Patil DY, Sandhya VK, Prakash KS, Surgihalli R, et al.
Outbreak of Kyasanur forest disease in Thirthahalli, Karnataka, India, 2014. Int J Infect Dis
Tandale BV, Balakrishnan A, Yadav PD, Marja N, Mourya DT. New focus of Kyasanur forest disease virus activity in a tribal area in Kerala, India, 2014. Infect Dis Poverty
Jha CS, Dutt CBS, Bawa KS. Deforestation and land use changes in Western Ghats, India. Curr Sci