Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research
  Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login  
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 1033       

   Table of Contents      
CLINICAL IMAGES
Year : 2016  |  Volume : 143  |  Issue : 2  |  Page : 249-250

Uncommon presentation of a less common tumour


1 Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh 160 012, India
2 Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh 160 012; Department of Dermatology & Venereology, All India Institute of Medical Sciences (AIIMS), Ansari Nagar New Delhi 110 029, India

Date of Web Publication14-Apr-2016

Correspondence Address:
Savita Yadav
Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh 160 012; Department of Dermatology & Venereology, All India Institute of Medical Sciences (AIIMS), Ansari Nagar New Delhi 110 029
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-5916.180233

Rights and Permissions

How to cite this article:
Vinay K, Yadav S. Uncommon presentation of a less common tumour . Indian J Med Res 2016;143:249-50

How to cite this URL:
Vinay K, Yadav S. Uncommon presentation of a less common tumour . Indian J Med Res [serial online] 2016 [cited 2020 May 31];143:249-50. Available from: http://www.ijmr.org.in/text.asp?2016/143/2/249/180233

A 44 yr old male, presented to the department of Dermatology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, in January 2012 with a large 25x15cm nodulo-ulcerative growth over the right chest wall destroying the nipple-areolar complex. The lesion showed central puckering with infiltrative margins, was hard in consistency, and fixed on the chest wall [Figure 1]. Contrast enhanced computed tomography showed small shadows in bilateral lung parenchyma, suggestive of lung metastasis [Figure 2]a and b. Skin punch biopsy showed clusters of tumour cells infiltrating dermis with desmoplasia and lymphovascular emboli [Figure 3]a. These cells were positive for oestrogen and progesterone receptors [Figure 3]b, c. A diagnosis of stage IV adenocarcinoma breast with cutaneous metastasis was made and palliative radiotherapy was administered. The patient died due to disease progression after four months.
Figure 1. Multiple nodular and nodulo-ulcerative lesions exclusively involving the right chest wall and abdomen with destruction of the nipple-areola complex. The largest lesion on the chest shows central puckering

Click here to view
Figure 2 . Lung window of CECT chest showing multiple, rounded, nodular lesions (arrows) suggestive of metastases (b) . Mediastinal window of CECT chest showing heterogenous attenuation soft tissue mass lesion involving right breast (arrow)

Click here to view
Figure 3. Microphotograph of skin biopsy showing tumour infiltrating the dermis with desmoplasia and lymphovascular emboli (inset, arrow) (a , H&E x 10x, 40x). The tumour cells showed uniform positive staining for oestrogen (b) , and progesterone (c) receptor (arrow) (DAB-Brown x 20x)

Click here to view


Male breast cancer is uncommon and direct extension into skin and surrounding structure can occur early but extensive and distant skin metastasis is rare. Increased awareness of cutaneous metastasis is necessary for early diagnosis and treatment.


   Acknowledgment Top


The authors acknowledge the contribution of Dr Uma Nahar Saikia, Professor, Department of Histopathology, PGIMER in histopathological diagnosis of the patient.


    Figures

  [Figure 1], [Figure 2], [Figure 3]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
   Acknowledgment
    Article Figures

 Article Access Statistics
    Viewed595    
    Printed6    
    Emailed0    
    PDF Downloaded224    
    Comments [Add]    

Recommend this journal