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CORRESPONDENCE
Year : 2016  |  Volume : 143  |  Issue : 2  |  Page : 247

Drug-induced diseases (DIDs)


Department of Pharmacology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly 243 001, Uttar Pradesh, India

Date of Web Publication14-Apr-2016

Correspondence Address:
Subodh Kumar
Department of Pharmacology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly 243 001, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-5916.180230

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How to cite this article:
Kumar S. Drug-induced diseases (DIDs). Indian J Med Res 2016;143:247

How to cite this URL:
Kumar S. Drug-induced diseases (DIDs). Indian J Med Res [serial online] 2016 [cited 2020 May 31];143:247. Available from: http://www.ijmr.org.in/text.asp?2016/143/2/247/180230

Sir,

Apropos of the article on DIDs in a tertiary care teaching hospital in India [1] , the authors have offered a different context for looking at adverse drug event related data. But, a few points in the article needs clarification. It has been stated that a total of 2381 adverse drug events (ADE) were evaluated and 924 cases of drug induced diseases (DID) were found. But, the criteria for differentiating between the two terms are not clear. Though a definition of both terms has been given, it does not help in identifying the key difference between the two. A clear cut distinction between the two should have been better. Further, the DID rate has been stated to be 38.9 per cent (24 out of 2381) which has been compared with two earlier studies [2],[3] . But the investigator of these studies have used different denominator for calculation of DID rate which is the number of patients evaluated rather than number of adverse events. Thus, these studies [2],[3] are not comparable with the present one [1] . It is erroneous to calculate DID from number of adverse drug events reported because it may underestimate the rate of DID as one patient may have more than one adverse events or oversestimate as all patients will not have adverse effects.

Conflicts of Interest: None.

 
   References Top

1.
Tandon VR, Khajuria V, Mahajan V, Sharma A, Gillani Z, Mahajan A. Drug-induced diseases (DIDs): An experience of a tertiary care teaching hospital from India. Indian J Med Res 2015; 142 : 33-9.  Back to cited text no. 1
    
2.
Atiqi R, van Bommel E, Cleophas TJ, Zwinderman AH. Prevalence of iatrogenic admissions to the Departments of Medicine/Cardiology/ Pulmonology in a 1,250 bed general hospital. Int J Clin Pharmacol Ther 2010; 48 : 517-24.  Back to cited text no. 2
    
3.
Imbs JL, Pouyanne P, Haramburu F, Welsch M, Decker N, Blayac JP, et al. Iatrogenic medication: estimation of its prevalence in French public hospitals. Regional Centers of Pharmacovigilance. Therapie 1999; 54 : 21-7.  Back to cited text no. 3
    




 

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