Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research
  Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login  
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 2760       
REVIEW ARTICLE
Year : 2015  |  Volume : 142  |  Issue : 6  |  Page : 647-654

Multiple sclerosis - New treatment modalities


1 Multiple Sclerosis Center, Department of Neurology, San Salvatore Hospital, L'Aquila, Italy
2 Department of Medicine, Health & Environment Sciences, University of L'Aquila, L'Aquila, Italy
3 Department of Clinical & Applied Sciences & Biotechnology, University of L'Aquila, L'Aquila, Italy

Correspondence Address:
Rocco Totaro
Multiple Sclerosis Center, Department of Neurology, San Salvatore Hospital, Via Vetoio 1, 67100 L'Aquila
Italy
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-5916.174543

Rights and Permissions

Ever since the introduction of the first disease modifying therapies, the concept of multiple sclerosis treatment algorithms developed ceaselessly. The increasing number of available drugs is paralleled by impelling issue of ensuring the most appropriate treatment to the right patient at the right time. The purpose of this review is to describe novel agents recently approved for multiple sclerosis treatment, namely teriflunomide, alemtuzumab and dimethylfumarate, focusing on mechanism of action, efficacy data in experimental setting, safety and tolerability. The place in therapy of newer treatment implies careful balancing of risk-benefit profile as well as accurate patient selection. Hence the widening of therapeutic arsenal provides greater opportunity for personalized therapy but also entails a complex trade-off between efficacy, tolerability, safety and eventually patient preference.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1805    
    Printed16    
    Emailed2    
    PDF Downloaded657    
    Comments [Add]    
    Cited by others 2    

Recommend this journal