Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research
  Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login  
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 276       

   Table of Contents      
BOOK REVIEW
Year : 2015  |  Volume : 142  |  Issue : 5  |  Page : 630-631

Endocrine tumor syndromes and their genetics


Date of Web Publication9-Dec-2015

Correspondence Address:
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

How to cite this article:
. Endocrine tumor syndromes and their genetics. Indian J Med Res 2015;142:630-1

How to cite this URL:
. Endocrine tumor syndromes and their genetics. Indian J Med Res [serial online] 2015 [cited 2020 May 27];142:630-1. Available from: http://www.ijmr.org.in/text.asp?2015/142/5/630/171332

Endocrine tumor syndromes and their genetics , C.A. Stratakis, editor (Karger, Basel, Switzerland) 2013. 188 pages. Price: US $ 221.00 / CHF 188.00

ISBN 978-3-318-02330-5

This book on the genetics of endocrine tumours has been authored by leading experts in the field. It is the 41 st volume of the ongoing series, 'Frontiers of Hormone Research'. The Chapter by J. A. Carney, 'Carney Triad' is a good example of how clinicians recognize unusual tumour syndromes and identify phenotypes which serve as the starting point of research into tumourigenesis. The chapters on common endocrine tumours such as familial non-medullary thyroid cancer and endocrine tumours in other familial neoplasia are interesting and welcome additions, and expand the spectrum of genetic disorders that predispose to endocrine tumours.

The chapters are well organized and coherent. Each chapter highlights the syndrome under consideration, a brief historical background, the constellation of clinical features and the underlying genetic abnormality. Wherever it is sorted out, the intracellular events that lead to tumourigenesis have been outlined. Wherever established, the genotype-phenotype correlation is presented clearly and where an individual phenotype has multiple predisposing genotypes the issue has been clarified. Each chapter has tables that present a summary of the chapter under consideration. The images are appropriate and of good quality. There are simplified diagrams which lead to a better understanding of cellular events in tumourigenesis. Each chapter outlines the indications for genetic testing, the current recommendations for screening relatives of the index case and the current recommendations regarding treatment. The rationale behind choosing therapeutic targets based on an understanding of the underlying pathophysiology and new potential therapeutic targets have been outlined.

To summarize, this book is a must read for physicians, paediatricians, endocrinologists and basic scientists.

M.S. Seshadri

Thirumalai Mission Hospital

Ranipet 632 404, India

mandalam.seshadri@gmail.com




 

Top
 
 
  Search
 
    Similar in PUBMED
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article

 Article Access Statistics
    Viewed215    
    Printed6    
    Emailed0    
    PDF Downloaded144    
    Comments [Add]    

Recommend this journal