Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research
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Year : 2015  |  Volume : 142  |  Issue : 3  |  Page : 301-310

Adherence to anti-retroviral therapy & factors associated with it: A community based cross-sectional study from West Bengal, India

1 Rabindra Bharati University, Directorate of Distance Education, Kolkata, India
2 Society for Positive Atmosphere & Related Support to HIV/AIDS (SPARSHA), Kolkata, India
3 National Institute of Cholera & Enteric Diseases (ICMR), Kolkata, India

Correspondence Address:
Samiran Panda
National Institute of Cholera & Enteric Diseases (ICMR), P-33 CIT Road, Scheme-XM, Beliaghta, Kolkata 700 010, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-5916.166595

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Background & objectives: Failure to adhere to anti-retroviral therapy (ART) can lead to a range of unfavourable consequences impacting upon people living with HIV (PLH) and society. It is, therefore, paramount that ART adherence is measured in a reliable manner and factors associated with adherence are identified. Lack of such data from West Bengal necessitated undertaking the current study. Methods: Participants were included during August-October, 2011 from three Drop-In-Centres (DICs) from the three districts of West Bengal, India. ART-adherence was calculated by using formula based on pill-count and records collected from ART-card in possession of each of the 128 consenting adult PLH. Information on self-reported adherence, socio-demography, and adherence influencing issues was also collected through interviewer-administered questionnaire. Results: Of the 128 PLH, 99 (77%) and 93 (73%) PLH had ≥90 per cent and ≥95 per cent adherence, respectively to ART. Conversely, subjective reporting captured much higher proportion of PLH as 'well adherent'; a finding having implications for ongoing ART programme. Factors, independently associated with poor adherence (<90%), were '7 th to 12 th month period of ART intake' (adjusted OR=9.5; 90% CI 1.9 - 47.3; p0 =0.02) and 'non-disclosure of HIV status to family members' (adjusted OR=4; 90% CI 1.3 - 13; P=0.05. Results at 95 per cent adherence cut-off were similar. Interpretation & conclusions: Enabling environment, which would encourage people to disclose their HIV status and in turn seek adherence partners from families and beyond and ongoing adherence-counselling appear to be important issues in the programme. Relevance of these study findings in wider context is conceivable.

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