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| CORRESPONDENCE |
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| Year : 2014 | Volume
: 139
| Issue : 6 | Page : 956-957 |
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Authors' response
Deep Dutta, Indira Maisnam, Ankit Shrivastava, Anirban Sinha, Sujoy Ghosh, Pradip Mukhopadhyay, Satinath Mukhopadhyay, Subhankar Chowdhury
Department of Endocrinology & Metabolism, Institute of Postgraduate Medical Education & Research & SSKM Hospital Kolkata 700 020, India
| Date of Web Publication | 4-Aug-2014 |
Correspondence Address:
Deep Dutta
Department of Endocrinology & Metabolism, Institute of Postgraduate Medical Education & Research & SSKM Hospital Kolkata 700 020
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 25265649 
How to cite this article:
Dutta D, Maisnam I, Shrivastava A, Sinha A, Ghosh S, Mukhopadhyay P, Mukhopadhyay S, Chowdhury S. Authors' response
. Indian J Med Res 2014;139:956-7 |
How to cite this URL:
Dutta D, Maisnam I, Shrivastava A, Sinha A, Ghosh S, Mukhopadhyay P, Mukhopadhyay S, Chowdhury S. Authors' response
. Indian J Med Res [serial online] 2014 [cited 2019 Dec 5];139:956-7. Available from: http://www.ijmr.org.in/text.asp?2014/139/6/956/138091 |
Sir,
The authors appreciate the comments of the esteemed reader of our article [1] . The authors agree with the observation that the occurrence of vitamin-D deficiency/insufficiency of 73.5 per cent (115/157) among individuals with prediabetes in our study was reflective of the widespread vitamin-D deficiency in the general population. The same has already been mentioned in the summary of the article in the last paragraph of the discussion section. The primary objective of this cross-sectional study was not to evaluate the burden of vitamin-D deficiency/insufficiency in prediabetes, but to highlight the inverse correlation between vitamin-D and insulin resistance, even after adjusting for body mass index and glycated haemoglobin. In a subsequent prospective study, we have observed vitamin-D to be predictive of prediabetes reversal to normoglycaemia [2] . Further, in the first open labelled randomized controlled trial from India, we observed vitamin-D supplementation to be beneficial in improving glycaemic outcomes in prediabetes and it was associated with improvement in insulin resistance, inflammatory cytokines and lipids [3] .
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| 1. | Dutta D, Maisnam I, Shrivastava A, Sinha A, Ghosh S, Mukhopadhyay P, et al. Serum vitamin-D predicts insulin resistance in individuals with prediabetes. Indian J Med Res 2013; 138 : 853-60. 
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| 2. | Dutta D, Choudhuri S, Mondal SA, Mukherjee S, Chowdhury S. Urine albumin creatinine ratio predicts prediabetes progression to diabetes and reversal to normoglycemia: Role of associated insulin resistance, inflammatory cytokines and low vitamin-D. J Diabetes 2013; doi: 10.1111/1753-0407.
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| 3. | Dutta D, Mondal SA, Choudhuri S, Maisnam I, Reza AHH, Bhattacharya B, et al. Vitamin-D supplementation in prediabetes reduced progression to type 2 diabetes and was associated with decreased insulin resistance and systemic inflammation: An open label randomized prospective study from Eastern India. Diabetes Res Clinical Pract 2014; 103 : e18-23.
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