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CORRESPONDENCE
Year : 2013  |  Volume : 138  |  Issue : 1  |  Page : 147

Should pyrazinamide be preferred in tuberculosis treatment during pregnancy?


Sakarya University, Faculty of Medicine, Department of Infectious Diseases & Clinical Microbiology, Sakarya, Turkey

Date of Web Publication6-Aug-2013

Correspondence Address:
Hasan Tahsin Gozdas
Sakarya University, Faculty of Medicine, Department of Infectious Diseases & Clinical Microbiology, Sakarya
Turkey
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Source of Support: None, Conflict of Interest: None


PMID: 24056570

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How to cite this article:
Karabay O, Gozdas HT. Should pyrazinamide be preferred in tuberculosis treatment during pregnancy?. Indian J Med Res 2013;138:147

How to cite this URL:
Karabay O, Gozdas HT. Should pyrazinamide be preferred in tuberculosis treatment during pregnancy?. Indian J Med Res [serial online] 2013 [cited 2020 Aug 15];138:147. Available from: http://www.ijmr.org.in/text.asp?2013/138/1/147/116205

Sir,

We have read the recent clinical image by Garg and Mohapatra [1] which is very interesting. They described a pregnant woman with tuberculosis who was treated with isoniazid, rifampicin, pyrazinamide and ethambutol for two months followed by isoniazid and rifampicin for four months. According to the current guidelines, the recommended treatment of tuberculosis in pregnancy is with isoniazid, rifampicin and ethambutol. Pyrazinamide is not recommended due to inadequate data on teratogenicity [2] . However, the authors detected mild intrauterine growth restriction in foetus by obstetrical ultrasound at presentation. They should clarify whether pyrazinamide is a suitable choice in tuberculosis treatment during pregnancy.

 
   References Top

1.Garg K, Mohapatra PR. A pregnant woman with dyspnoea, fever & decreased vision. Indian J Med Res 2012; 136 : 1062.   Back to cited text no. 1
[PUBMED]    
2.Antimycobacterial therapy. In: Gilbert DN, Moellering RC Jr, Eliopoulos GM, Chambers HF, Saag MS, editors. The Sanford guide to antimicrobial therapy, 42 nd ed. Sperryville, VA: Antimicrobial Therapy, Inc.; 2012. p. 130.  Back to cited text no. 2
    




 

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