Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research Indan Journal of Medical Research
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REVIEW ARTICLE
Year : 2012  |  Volume : 136  |  Issue : 6  |  Page : 926-941

Controversies in the use & implementation of drug-eluting stent technology


1 Regional Cardiac Cath Lab & Department of Cardiology, Kaiser Permanente, Los Angeles, CA, USA
2 Regional Cardiac Cath Lab & Department of Cardiology, Kaiser Permanente, Los Angeles; Department of Research & Evaluation, Kaiser Permanente, Pasadena, CA, USA

Correspondence Address:
Somjot S Brar
Director of Vascular Medicine, 4867 Sunset Blvd., Rm. 3755, Los Angeles, CA 90027
USA
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Source of Support: None, Conflict of Interest: None


PMID: 23391788

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The introduction of drug eluting stents has resulted in dramatic reductions in the rates of restenosis and the need for repeat revascularization. In the last several years, concern has been raised regarding the long-term safety of this technology, particularly in the area of late restenosis and stent thrombosis. The development of newer anti-restenotic drug coatings, biodegradable polymers and even completely bioabsorbable stents offer the potential to address these limitations. Additional questions that have recently come to the forefront include the optimal duration of dual antiplatelet therapy, the use of platelet reactivity assays and genetic testing and drug eluting stent use in the treatment of acute myocardial infarction. This article will attempt to address these and other areas of controversy in the use and implementation of drug eluting stents.


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