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ORIGINAL ARTICLE
Year : 2011  |  Volume : 134  |  Issue : 6  |  Page : 950-953

Prevalence of HIV among blood donors in a tertiary care centre of north India


Department of Transfusion Medicine, Indraprastha Apollo Hospitals, New Delhi, India

Correspondence Address:
R N Makroo
Director, Department of Transfusion Medicine, Gate No.9, Indraprastha Apollo Hospital, Sarita Vihar, Mathura Road, New Delhi 110 044
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-5916.92640

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Background & objectives: India has the second highest HIV population in the world with about 2.5-3.0 million cases. HIV-2 cases among general and blood donor population have also been reported mostly from west and south India. This single centre study was carried out to observe the HIV-1 and HIV-2 prevalence among blood donors from north India. Methods: A total of 2,04,677 people were screened for the presence of HIV infection over the 11 year period (1999 to 2009). Till 2004, a third generation ELISA kit was used. From 2005 till January 2009 all tests were done using the fourth generation ELISA kit which detected the presence of HIV-1 P24 antigen and anti-HIV antibodies. From February 2009 onwards, the kits used were Genscreen ULTRA HIV Ag-Ab Assay. Results: A total of 506 (0.247%) donors were found to be repeat reactive for HIV. Of these, 486 (96%) donors tested using the Western blot were found positive for HIV-1 infection. Twenty (4%) donors showed a negative Western blot result, none of the donors were found reactive for HIV-2 infection. Interpretation & conclusions: The prevalence of HIV was 0.249 per cent among blood donors of north India. No HIV-2 case was found among the studied blood donor population indicating that it is not a threat currently.


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